Team game results - 2021 Pittsburgh Pirates
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/16/2021 | | | Was | W | 21-5 | | Wheeler, Z | R | Wheeler, Z | Stripling, R | Urias, J | L |
| 4/17/2021 | | | Was | W | 7-4 | | Giolito, L | R | Giolito, L | | Gonsolin, T | R |
| 4/18/2021 | | | Was | W | 8-7 | | Weaver, L | R | Weaver, L | Jeffress, J | Eflin, Z | R |
| 4/19/2021 | | @ | Was | L | 8-12 | | Hudson, D | R | Hudson, D | | Paddack, C | R |
| 4/20/2021 | | @ | Was | W | 10-2 | | Burnes, C | R | Burnes, C | Stripling, R | Sanchez, S | R |
| 4/21/2021 | | @ | Was | W | 6-2 | | Wheeler, Z | R | Wheeler, Z | Hader, J | Urias, J | L |
| 4/23/2021 | | @ | Mia | L | 0-3 | | Giolito, L | R | Giolito, L | | Ryu, H | L |
| 4/24/2021 | | @ | Mia | W | 2-1 | | Weaver, L | R | Weaver, L | Jeffress, J | Fiers, M | R |
| 4/25/2021 | | @ | Mia | W | 3-0 | | Hudson, D | R | Hader, J | Jeffress, J | Anderson, T | L |
| 4/26/2021 | | | Mia | L | 2-3 | | Burnes, C | R | Jeffress, J | | Miley, W | L |
| 4/27/2021 | | | Mia | L | 4-9 | | Wheeler, Z | R | Wheeler, Z | | Hendricks, K | R |
| 4/28/2021 | | | Mia | W | 7-5 | | Giolito, L | R | Giolito, L | Hader, J | Ryu, H | L |
| 4/29/2021 | | @ | Cin | W | 3-2 | | Weaver, L | R | Weaver, L | Jeffress, J | Gray, S | R |
| 4/30/2021 | | @ | Cin | L | 2-6 | | Hudson, D | R | Hudson, D | | Anderson, B | L |
| 5/1/2021 | | @ | Cin | L | 7-8 | | Burnes, C | R | Jeffress, J | | Shoemaker, M | R |
| 5/2/2021 | | | Cin | W | 7-3 | | Wheeler, Z | R | Wheeler, Z | | deGrom, J | R |
| 5/3/2021 | | | Cin | W | 4-3 | 11 | Giolito, L | R | Hader, J | | Davies, Z | R |
| 5/4/2021 | | | Cin | W | 10-9 | | Weaver, L | R | Hatch, T | | Gray, S | R |
| 5/6/2021 | | @ | SF | W | 7-2 | | Hudson, D | R | Hudson, D | | Marquez, G | R |
| 5/7/2021 | | @ | SF | W | 11-2 | | Burnes, C | R | Burnes, C | | Wainwright, A | R |
| 5/8/2021 | | @ | SF | W | 3-1 | | Wheeler, Z | R | Wheeler, Z | Jeffress, J | Castillo, L | R |
| 5/9/2021 | | | SF | L | 1-6 | | Giolito, L | R | Giolito, L | | Gallen, Z | R |
| 5/10/2021 | | | SF | L | 4-9 | | Weaver, L | R | Weaver, L | | Lorenzen, M | R |
| 5/11/2021 | | | SF | W | 5-2 | | Hudson, D | R | Hudson, D | Jeffress, J | Marquez, G | R |
| 5/12/2021 | | | NYM | W | 6-1 | | Burnes, C | R | Burnes, C | | Brubaker, J | R |
| 5/13/2021 | | | NYM | W | 6-1 | | Wheeler, Z | R | Wheeler, Z | | Alcantara, S | R |
| 5/14/2021 | | | NYM | W | 5-0 | | Giolito, L | R | Giolito, L | | Musgrove, J | R |
| 5/15/2021 | | @ | NYM | L | 1-5 | | Weaver, L | R | Weaver, L | | Peterson, D | L |
| 5/16/2021 | | @ | NYM | L | 3-4 | | Hudson, D | R | Hudson, D | | Nola, A | R |
| 5/17/2021 | | @ | NYM | W | 17-1 | | Burnes, C | R | Burnes, C | | Brubaker, J | R |
| 5/19/2021 | | @ | ChN | W | 7-6 | | Wheeler, Z | R | Hatch, T | Jeffress, J | Fried, M | L |
| 5/20/2021 | | @ | ChN | L | 1-9 | | Giolito, L | R | Giolito, L | | Mahle, T | R |
| 5/21/2021 | | @ | ChN | W | 7-4 | | Weaver, L | R | Weaver, L | Jeffress, J | Freeland, K | L |
| 5/22/2021 | | | ChN | W | 11-2 | | Buehler, W | R | Buehler, W | | Richards, G | R |
| 5/23/2021 | | | ChN | W | 15-1 | | Burnes, C | R | Smith, R | | Woodruff, B | R |
| 5/24/2021 | | | ChN | W | 6-5 | | Wheeler, Z | R | Williams, D | Jeffress, J | Gray, J | R |
| 5/26/2021 | | | StL | W | 3-2 | 10 | Giolito, L | R | Smith, R | | Lynn, L | R |
| 5/27/2021 | | | StL | W | 2-1 | | Weaver, L | R | Weaver, L | Hader, J | Gausman, K | R |
| 5/28/2021 | | | StL | L | 2-3 | | Buehler, W | R | Buehler, W | | Morton, C | R |
| 5/29/2021 | | @ | StL | W | 11-2 | | Wheeler, Z | R | Wheeler, Z | | Cole, G | R |
| 5/30/2021 | | @ | StL | W | 5-4 | | Burnes, C | R | Williams, D | Hader, J | Kuhl, C | R |
| 5/31/2021 | | @ | StL | W | 19-4 | | Giolito, L | R | Giolito, L | | Lynn, L | R |
| 6/1/2021 | | @ | Mil | L | 8-13 | | Weaver, L | R | Weaver, L | | Lindblom, J | R |
| 6/2/2021 | | @ | Mil | W | 4-3 | | Buehler, W | R | Buehler, W | Jeffress, J | Newcomb, S | L |
| 6/3/2021 | | @ | Mil | W | 8-6 | 10 | Wheeler, Z | R | Jeffress, J | Hader, J | Rogers, T | L |
| 6/4/2021 | | | Mil | L | 6-7 | 11 | Burnes, C | R | Smith, R | | Lamet, D | R |
| 6/5/2021 | | | Mil | W | 4-3 | 10 | Giolito, L | R | Jeffress, J | | Cueto, J | R |
| 6/6/2021 | | | Mil | W | 10-9 | | Weaver, L | R | Weaver, L | Crichton, S | Lindblom, J | R |
| 6/8/2021 | | | Atl | W | 8-4 | | Buehler, W | R | Buehler, W | | Sanchez, A | R |
| 6/9/2021 | | | Atl | W | 7-2 | | Wheeler, Z | R | Wheeler, Z | | Wright, K | R |
| 6/10/2021 | | | Atl | W | 4-3 | 13 | Giolito, L | R | Parker, B | | Fedde, E | R |
| 6/11/2021 | | @ | Atl | L | 7-8 | | Weaver, L | R | Weaver, L | | Glasnow, T | R |
| 6/12/2021 | | @ | Atl | W | 7-3 | | Burnes, C | R | Burnes, C | | Heaney, A | L |
| 6/13/2021 | | @ | Atl | L | 7-8 | 10 | Wheeler, Z | R | Crichton, S | | Sanchez, A | R |
| 6/15/2021 | | @ | Tor | W | 5-3 | | Giolito, L | R | Giolito, L | Jeffress, J | Lopez, P | R |
| 6/16/2021 | | @ | Tor | W | 5-3 | | Buehler, W | R | Buehler, W | Hader, J | Scherzer, M | R |
| 6/17/2021 | | @ | Tor | W | 7-4 | | Burnes, C | R | Burnes, C | Jeffress, J | Flaherty, J | R |
| 6/18/2021 | | | Tor | L | 5-6 | | Hudson, D | R | Hudson, D | | Darvish, Y | R |
| 6/19/2021 | | | Tor | W | 12-1 | | Wheeler, Z | R | Wheeler, Z | | Velasquez, V | R |
| 6/20/2021 | | | Tor | W | 8-5 | | Giolito, L | R | Giolito, L | Hader, J | Corbin, P | L |
| 6/22/2021 | | | LA | W | 4-0 | | Buehler, W | R | Buehler, W | | Bauer, T | R |
| 6/23/2021 | | | LA | L | 1-3 | | Hudson, D | R | Hudson, D | | Maeda, K | R |
| 6/24/2021 | | | LA | W | 4-2 | | Weaver, L | R | Weaver, L | Jeffress, J | Kershaw, C | L |
| 6/25/2021 | | @ | LA | L | 6-9 | | Wheeler, Z | R | Smith, R | | Senzatela, A | R |
| 6/26/2021 | | @ | LA | L | 3-5 | | Giolito, L | R | Bradley, A | | Smith, C | L |
| 6/27/2021 | | @ | LA | L | 1-3 | | Buehler, W | R | Buehler, W | | Bauer, T | R |
| 7/3/2021 | | @ | Atl | W | 6-3 | | Giolito, L | R | Smith, R | | Heaney, A | L |
| 7/4/2021 | | @ | Atl | W | 20-4 | | Buehler, W | R | Buehler, W | | Sanchez, A | R |
| 7/5/2021 | | @ | Atl | L | 6-7 | | Weaver, L | R | Jeffress, J | | Glasnow, T | R |
| 7/6/2021 | | | Atl | W | 9-2 | | Hudson, D | R | Hudson, D | | May, D | R |
| 7/7/2021 | | | Atl | W | 11-9 | | Oviedo, J | R | Oviedo, J | Hader, J | Fedde, E | R |
| 7/8/2021 | | | Atl | W | 8-3 | | Giolito, L | R | Giolito, L | | Wright, K | R |
| 7/9/2021 | | | Mia | W | 5-1 | | Burnes, C | R | Burnes, C | | Ryu, H | L |
| 7/10/2021 | | | Mia | L | 7-9 | | Buehler, W | R | Buehler, W | | Fiers, M | R |
| 7/11/2021 | | | Mia | W | 10-1 | | Hudson, D | R | Hudson, D | | Anderson, T | L |
| 7/13/2021 | | @ | Mia | L | 10-12 | | Weaver, L | R | Weaver, L | | Miley, W | L |
| 7/14/2021 | | @ | Mia | W | 7-2 | | Giolito, L | R | Giolito, L | | Roark, T | R |
| 7/15/2021 | | @ | Mia | W | 3-1 | | Burnes, C | R | Burnes, C | Hader, J | Hendricks, K | R |
| 7/16/2021 | | | LA | W | 10-0 | | Wheeler, Z | R | Wheeler, Z | | Bauer, T | R |
| 7/17/2021 | | | LA | L | 5-14 | | Buehler, W | R | Buehler, W | | Maeda, K | R |
| 7/18/2021 | | | LA | L | 2-8 | | Weaver, L | R | Weaver, L | | Kershaw, C | L |
| 7/19/2021 | | @ | LA | W | 5-3 | | Giolito, L | R | Giolito, L | Jeffress, J | Senzatela, A | R |
| 7/20/2021 | | @ | LA | L | 1-3 | | Burnes, C | R | Burnes, C | | Mills, A | R |
| 7/21/2021 | | @ | LA | W | 4-2 | 10 | Wheeler, Z | R | Parker, B | Hader, J | Bauer, T | R |
| 7/23/2021 | | | StL | W | 4-1 | 10 | Buehler, W | R | Williams, D | | Lynn, L | R |
| 7/24/2021 | | | StL | L | 7-8 | | Weaver, L | R | Weaver, L | | Cole, G | R |
| 7/25/2021 | | | StL | L | 4-6 | | Giolito, L | R | Giolito, L | | Gausman, K | R |
| 7/26/2021 | | @ | StL | W | 4-0 | | Wheeler, Z | R | Wheeler, Z | Hader, J | Kuhl, C | R |
| 7/27/2021 | | @ | StL | W | 5-2 | | Burnes, C | R | Burnes, C | Jeffress, J | Castellani, R | R |
| 7/28/2021 | | @ | StL | W | 8-7 | 10 | Buehler, W | R | Williams, D | Hader, J | Lynn, L | R |
| 7/29/2021 | | @ | NYM | L | 5-6 | | Weaver, L | R | Weaver, L | | Nola, A | R |
| 7/30/2021 | | @ | NYM | W | 7-4 | | Giolito, L | R | Giolito, L | | Musgrove, J | R |
| 7/31/2021 | | @ | NYM | W | 12-4 | | Wheeler, Z | R | Wheeler, Z | | Brubaker, J | R |
| 8/1/2021 | | | NYM | W | 5-4 | | Burnes, C | R | Burnes, C | Hader, J | Brubaker, J | R |
| 8/2/2021 | | | NYM | W | 7-0 | | Buehler, W | R | Buehler, W | | Peterson, D | L |
| 8/3/2021 | | | NYM | W | 4-1 | | Weaver, L | R | Weaver, L | Hader, J | Nola, A | R |
| 8/5/2021 | | | ChN | L | 0-5 | | Wheeler, Z | R | Wheeler, Z | | Fried, M | L |
| 8/6/2021 | | | ChN | W | 5-2 | | Giolito, L | R | Giolito, L | Jeffress, J | Gray, J | R |
| 8/7/2021 | | | ChN | W | 7-5 | | Buehler, W | R | Parker, B | Hader, J | Mahle, T | R |
| 8/8/2021 | | @ | ChN | W | 5-4 | | Burnes, C | R | Smith, R | Hader, J | Woodruff, B | R |
| 8/9/2021 | | @ | ChN | L | 3-9 | | Weaver, L | R | Weaver, L | | Webb, L | R |
| 8/10/2021 | | @ | ChN | L | 5-6 | | Wheeler, Z | R | Williams, D | | Fried, M | L |
| 8/11/2021 | | @ | Mil | W | 10-1 | | Giolito, L | R | Giolito, L | Hatch, T | Antone, T | R |
| 8/12/2021 | | @ | Mil | W | 5-3 | | Buehler, W | R | Buehler, W | Jeffress, J | Cueto, J | R |
| 8/13/2021 | | @ | Mil | W | 8-0 | | Burnes, C | R | Burnes, C | | Lindblom, J | R |
| 8/14/2021 | | | Mil | L | 7-12 | | Weaver, L | R | Kolarek, A | | Rogers, T | L |
| 8/15/2021 | | | Mil | W | 3-2 | | Wheeler, Z | R | Wheeler, Z | Hader, J | Lamet, D | R |
| 8/16/2021 | | | Mil | W | 9-8 | | Giolito, L | R | Hatch, T | Hader, J | Peralta, F | R |
| 8/18/2021 | | | Cin | W | 5-2 | | Burnes, C | R | Burnes, C | Kolarek, A | Davies, Z | R |
| 8/19/2021 | | | Cin | L | 4-8 | | Hudson, D | R | Hudson, D | | Gray, S | R |
| 8/20/2021 | | | Cin | L | 4-10 | 11 | Wheeler, Z | R | Crichton, S | | Brault, S | L |
| 8/21/2021 | | @ | Cin | L | 7-12 | | Giolito, L | R | Giolito, L | | deGrom, J | R |
| 8/22/2021 | | @ | Cin | L | 7-10 | | Weaver, L | R | Hatch, T | | Anderson, B | L |
| 8/23/2021 | | @ | Cin | L | 2-8 | | Burnes, C | R | Burnes, C | | Davies, Z | R |
| 8/24/2021 | | @ | Tor | W | 8-0 | | Hudson, D | R | Hudson, D | | Corbin, P | L |
| 8/25/2021 | | @ | Tor | L | 3-6 | | Wheeler, Z | R | Wheeler, Z | | Darvish, Y | R |
| 8/26/2021 | | @ | Tor | W | 6-4 | | Giolito, L | R | Giolito, L | Hader, J | Lopez, P | R |
| 8/27/2021 | | | Tor | L | 4-5 | | Weaver, L | R | Weaver, L | | Flaherty, J | R |
| 8/28/2021 | | | Tor | W | 4-1 | | Burnes, C | R | Burnes, C | Jeffress, J | Scherzer, M | R |
| 8/29/2021 | | | Tor | W | 4-0 | | Hudson, D | R | Kolarek, A | | Corbin, P | L |
| 8/31/2021 | | | SF | W | 9-5 | | Wheeler, Z | R | Wheeler, Z | | Gallen, Z | R |
| 9/1/2021 | | | SF | W | 10-8 | | Giolito, L | R | Parker, B | Hader, J | Castillo, L | R |
| 9/2/2021 | | | SF | L | 7-8 | | Burnes, C | R | Smith, R | | Marquez, G | R |
| 9/3/2021 | | @ | SF | L | 3-5 | 11 | Hudson, D | R | Kolarek, A | | Wainwright, A | R |
| 9/4/2021 | | @ | SF | W | 10-8 | | Weaver, L | R | Kolarek, A | Hader, J | Ponce de Leon, D | R |
| 9/5/2021 | | @ | SF | L | 2-3 | | Wheeler, Z | R | Wheeler, Z | | Gallen, Z | R |
| 9/7/2021 | | @ | Was | W | 5-3 | | Burnes, C | R | Burnes, C | | Eflin, Z | R |
| 9/8/2021 | | @ | Was | L | 3-9 | | Giolito, L | R | Giolito, L | | Young, A | L |
| 9/9/2021 | | @ | Was | W | 2-1 | | Hudson, D | R | Smith, R | Hader, J | Urias, J | L |
| 9/10/2021 | | | Was | W | 13-11 | 11 | Weaver, L | R | Hader, J | | Paddack, C | R |
| 9/11/2021 | | | Was | L | 1-5 | | Wheeler, Z | R | Wheeler, Z | | Clarke, T | R |
| 9/12/2021 | | | Was | W | 9-8 | | Oviedo, J | R | Bradley, A | Williams, D | Teheran, J | R |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/16/2021 | | | Was | W | Frazier, T | 21 | 5 | 1 | 0 | 1.000 | 1-0 | W1 | 1 |
| 4/17/2021 | | | Was | W | Hosmer, E | 7 | 4 | 2 | 0 | 1.000 | 2-0 | W2 | 2 |
| 4/18/2021 | | | Was | W | Myers, W | 8 | 7 | 3 | 0 | 1.000 | 3-0 | W3 | 3 |
| 4/19/2021 | | @ | Was | L | | 8 | 12 | 3 | 1 | .750 | 3-1 | L1 | 4 |
| 4/20/2021 | | @ | Was | W | Seager, C | 10 | 2 | 4 | 1 | .800 | 4-1 | W1 | 5 |
| 4/21/2021 | | @ | Was | W | Rendon, A | 6 | 2 | 5 | 1 | .833 | 5-1 | W2 | 6 |
| 4/23/2021 | | @ | Mia | L | | 0 | 3 | 5 | 2 | .714 | 5-2 | L1 | 7 |
| 4/24/2021 | | @ | Mia | W | Hampson, G | 2 | 1 | 6 | 2 | .750 | 6-2 | W1 | 8 |
| 4/25/2021 | | @ | Mia | W | Seager, C | 3 | 0 | 7 | 2 | .778 | 7-2 | W2 | 9 |
| 4/26/2021 | | | Mia | L | | 2 | 3 | 7 | 3 | .700 | 7-3 | L1 | 10 |
| 4/27/2021 | | | Mia | L | | 4 | 9 | 7 | 4 | .636 | 6-4 | L2 | 11 |
| 4/28/2021 | | | Mia | W | Casali, C | 7 | 5 | 8 | 4 | .667 | 6-4 | W1 | 12 |
| 4/29/2021 | | @ | Cin | W | Yastrzemski, M | 3 | 2 | 9 | 4 | .692 | 6-4 | W2 | 13 |
| 4/30/2021 | | @ | Cin | L | | 2 | 6 | 9 | 5 | .643 | 6-4 | L1 | 14 |
| 5/1/2021 | | @ | Cin | L | | 7 | 8 | 9 | 6 | .600 | 5-5 | L2 | 15 |
| 5/2/2021 | | | Cin | W | Nimmo, B | 7 | 3 | 10 | 6 | .625 | 5-5 | W1 | 16 |
| 5/3/2021 | | | Cin | W | Meadows, A | 4 | 3 | 11 | 6 | .647 | 6-4 | W2 | 17 |
| 5/4/2021 | | | Cin | W | Casali, C | 10 | 9 | 12 | 6 | .667 | 6-4 | W3 | 18 |
| 5/6/2021 | | @ | SF | W | Belt, B | 7 | 2 | 13 | 6 | .684 | 6-4 | W4 | 19 |
| 5/7/2021 | | @ | SF | W | Yastrzemski, M | 11 | 2 | 14 | 6 | .700 | 7-3 | W5 | 20 |
| 5/8/2021 | | @ | SF | W | Nimmo, B | 3 | 1 | 15 | 6 | .714 | 8-2 | W6 | 21 |
| 5/9/2021 | | | SF | L | | 1 | 6 | 15 | 7 | .682 | 7-3 | L1 | 22 |
| 5/10/2021 | | | SF | L | | 4 | 9 | 15 | 8 | .652 | 6-4 | L2 | 23 |
| 5/11/2021 | | | SF | W | Myers, W | 5 | 2 | 16 | 8 | .667 | 7-3 | W1 | 24 |
| 5/12/2021 | | | NYM | W | Myers, W | 6 | 1 | 17 | 8 | .680 | 8-2 | W2 | 25 |
| 5/13/2021 | | | NYM | W | Hosmer, E | 6 | 1 | 18 | 8 | .692 | 8-2 | W3 | 26 |
| 5/14/2021 | | | NYM | W | Muncy, M | 5 | 0 | 19 | 8 | .704 | 8-2 | W4 | 27 |
| 5/15/2021 | | @ | NYM | L | | 1 | 5 | 19 | 9 | .679 | 7-3 | L1 | 28 |
| 5/16/2021 | | @ | NYM | L | | 3 | 4 | 19 | 10 | .655 | 6-4 | L2 | 29 |
| 5/17/2021 | | @ | NYM | W | Myers, W | 17 | 1 | 20 | 10 | .667 | 6-4 | W1 | 30 |
| 5/19/2021 | | @ | ChN | W | Rendon, A | 7 | 6 | 21 | 10 | .677 | 6-4 | W2 | 31 |
| 5/20/2021 | | @ | ChN | L | | 1 | 9 | 21 | 11 | .656 | 6-4 | L1 | 32 |
| 5/21/2021 | | @ | ChN | W | Rendon, A | 7 | 4 | 22 | 11 | .667 | 7-3 | W1 | 33 |
| 5/22/2021 | | | ChN | W | | 11 | 2 | 23 | 11 | .676 | 7-3 | W2 | 34 |
| 5/23/2021 | | | ChN | W | Nimmo, B | 15 | 1 | 24 | 11 | .686 | 7-3 | W3 | 35 |
| 5/24/2021 | | | ChN | W | Flores, W | 6 | 5 | 25 | 11 | .694 | 7-3 | W4 | 36 |
| 5/26/2021 | | | StL | W | Belt, B | 3 | 2 | 26 | 11 | .703 | 7-3 | W5 | 37 |
| 5/27/2021 | | | StL | W | Seager, C | 2 | 1 | 27 | 11 | .711 | 8-2 | W6 | 38 |
| 5/28/2021 | | | StL | L | | 2 | 3 | 27 | 12 | .692 | 8-2 | L1 | 39 |
| 5/29/2021 | | @ | StL | W | Seager, C | 11 | 2 | 28 | 12 | .700 | 8-2 | W1 | 40 |
| 5/30/2021 | | @ | StL | W | Myers, W | 5 | 4 | 29 | 12 | .707 | 8-2 | W2 | 41 |
| 5/31/2021 | | @ | StL | W | Belt, B | 19 | 4 | 30 | 12 | .714 | 9-1 | W3 | 42 |
| 6/1/2021 | | @ | Mil | L | | 8 | 13 | 30 | 13 | .698 | 8-2 | L1 | 43 |
| 6/2/2021 | | @ | Mil | W | | 4 | 3 | 31 | 13 | .705 | 8-2 | W1 | 44 |
| 6/3/2021 | | @ | Mil | W | Seager, C | 8 | 6 | 32 | 13 | .711 | 8-2 | W2 | 45 |
| 6/4/2021 | | | Mil | L | | 6 | 7 | 32 | 14 | .696 | 7-3 | L1 | 46 |
| 6/5/2021 | | | Mil | W | Myers, W | 4 | 3 | 33 | 14 | .702 | 7-3 | W1 | 47 |
| 6/6/2021 | | | Mil | W | Rendon, A | 10 | 9 | 34 | 14 | .708 | 7-3 | W2 | 48 |
| 6/8/2021 | | | Atl | W | Meadows, A | 8 | 4 | 35 | 14 | .714 | 8-2 | W3 | 49 |
| 6/9/2021 | | | Atl | W | Myers, W | 7 | 2 | 36 | 14 | .720 | 8-2 | W4 | 50 |
| 6/10/2021 | | | Atl | W | Flores, W | 4 | 3 | 37 | 14 | .725 | 8-2 | W5 | 51 |
| 6/11/2021 | | @ | Atl | L | | 7 | 8 | 37 | 15 | .712 | 7-3 | L1 | 52 |
| 6/12/2021 | | @ | Atl | W | Myers, W | 7 | 3 | 38 | 15 | .717 | 8-2 | W1 | 53 |
| 6/13/2021 | | @ | Atl | L | | 7 | 8 | 38 | 16 | .704 | 7-3 | L1 | 54 |
| 6/15/2021 | | @ | Tor | W | Belt, B | 5 | 3 | 39 | 16 | .709 | 7-3 | W1 | 55 |
| 6/16/2021 | | @ | Tor | W | | 5 | 3 | 40 | 16 | .714 | 8-2 | W2 | 56 |
| 6/17/2021 | | @ | Tor | W | Myers, W | 7 | 4 | 41 | 16 | .719 | 8-2 | W3 | 57 |
| 6/18/2021 | | | Tor | L | | 5 | 6 | 41 | 17 | .707 | 7-3 | L1 | 58 |
| 6/19/2021 | | | Tor | W | Muncy, M | 12 | 1 | 42 | 17 | .712 | 7-3 | W1 | 59 |
| 6/20/2021 | | | Tor | W | Seager, C | 8 | 5 | 43 | 17 | .717 | 7-3 | W2 | 60 |
| 6/22/2021 | | | LA | W | Belt, B | 4 | 0 | 44 | 17 | .721 | 7-3 | W3 | 61 |
| 6/23/2021 | | | LA | L | | 1 | 3 | 44 | 18 | .710 | 7-3 | L1 | 62 |
| 6/24/2021 | | | LA | W | Hosmer, E | 4 | 2 | 45 | 18 | .714 | 7-3 | W1 | 63 |
| 6/25/2021 | | @ | LA | L | | 6 | 9 | 45 | 19 | .703 | 7-3 | L1 | 64 |
| 6/26/2021 | | @ | LA | L | | 3 | 5 | 45 | 20 | .692 | 6-4 | L2 | 65 |
| 6/27/2021 | | @ | LA | L | | 1 | 3 | 45 | 21 | .682 | 5-5 | L3 | 66 |
| 7/3/2021 | | @ | Atl | W | Frazier, T | 6 | 3 | 46 | 21 | .687 | 5-5 | W1 | 67 |
| 7/4/2021 | | @ | Atl | W | Belt, B | 20 | 4 | 47 | 21 | .691 | 6-4 | W2 | 68 |
| 7/5/2021 | | @ | Atl | L | | 6 | 7 | 47 | 22 | .681 | 5-5 | L1 | 69 |
| 7/6/2021 | | | Atl | W | Nimmo, B | 9 | 2 | 48 | 22 | .686 | 5-5 | W1 | 70 |
| 7/7/2021 | | | Atl | W | Meadows, A | 11 | 9 | 49 | 22 | .690 | 5-5 | W2 | 71 |
| 7/8/2021 | | | Atl | W | Myers, W | 8 | 3 | 50 | 22 | .694 | 6-4 | W3 | 72 |
| 7/9/2021 | | | Mia | W | Casali, C | 5 | 1 | 51 | 22 | .699 | 6-4 | W4 | 73 |
| 7/10/2021 | | | Mia | L | | 7 | 9 | 51 | 23 | .689 | 6-4 | L1 | 74 |
| 7/11/2021 | | | Mia | W | Myers, W | 10 | 1 | 52 | 23 | .693 | 7-3 | W1 | 75 |
| 7/13/2021 | | @ | Mia | L | | 10 | 12 | 52 | 24 | .684 | 7-3 | L1 | 76 |
| 7/14/2021 | | @ | Mia | W | Flores, W | 7 | 2 | 53 | 24 | .688 | 7-3 | W1 | 77 |
| 7/15/2021 | | @ | Mia | W | Yastrzemski, M | 3 | 1 | 54 | 24 | .692 | 7-3 | W2 | 78 |
| 7/16/2021 | | | LA | W | Seager, C | 10 | 0 | 55 | 24 | .696 | 8-2 | W3 | 79 |
| 7/17/2021 | | | LA | L | | 5 | 14 | 55 | 25 | .688 | 7-3 | L1 | 80 |
| 7/18/2021 | | | LA | L | | 2 | 8 | 55 | 26 | .679 | 6-4 | L2 | 81 |
| 7/19/2021 | | @ | LA | W | Belt, B | 5 | 3 | 56 | 26 | .683 | 6-4 | W1 | 82 |
| 7/20/2021 | | @ | LA | L | | 1 | 3 | 56 | 27 | .675 | 5-5 | L1 | 83 |
| 7/21/2021 | | @ | LA | W | Hosmer, E | 4 | 2 | 57 | 27 | .679 | 6-4 | W1 | 84 |
| 7/23/2021 | | | StL | W | Belt, B | 4 | 1 | 58 | 27 | .682 | 6-4 | W2 | 85 |
| 7/24/2021 | | | StL | L | | 7 | 8 | 58 | 28 | .674 | 6-4 | L1 | 86 |
| 7/25/2021 | | | StL | L | | 4 | 6 | 58 | 29 | .667 | 5-5 | L2 | 87 |
| 7/26/2021 | | @ | StL | W | Seager, C | 4 | 0 | 59 | 29 | .670 | 5-5 | W1 | 88 |
| 7/27/2021 | | @ | StL | W | Meadows, A | 5 | 2 | 60 | 29 | .674 | 5-5 | W2 | 89 |
| 7/28/2021 | | @ | StL | W | Flores, W | 8 | 7 | 61 | 29 | .678 | 6-4 | W3 | 90 |
| 7/29/2021 | | @ | NYM | L | | 5 | 6 | 61 | 30 | .670 | 6-4 | L1 | 91 |
| 7/30/2021 | | @ | NYM | W | Hampson, G | 7 | 4 | 62 | 30 | .674 | 6-4 | W1 | 92 |
| 7/31/2021 | | @ | NYM | W | Hampson, G | 12 | 4 | 63 | 30 | .677 | 7-3 | W2 | 93 |
| 8/1/2021 | | | NYM | W | Yastrzemski, M | 5 | 4 | 64 | 30 | .681 | 7-3 | W3 | 94 |
| 8/2/2021 | | | NYM | W | Rendon, A | 7 | 0 | 65 | 30 | .684 | 7-3 | W4 | 95 |
| 8/3/2021 | | | NYM | W | Belt, B | 4 | 1 | 66 | 30 | .688 | 8-2 | W5 | 96 |
| 8/5/2021 | | | ChN | L | | 0 | 5 | 66 | 31 | .680 | 8-2 | L1 | 97 |
| 8/6/2021 | | | ChN | W | Seager, C | 5 | 2 | 67 | 31 | .684 | 8-2 | W1 | 98 |
| 8/7/2021 | | | ChN | W | Seager, C | 7 | 5 | 68 | 31 | .687 | 8-2 | W2 | 99 |
| 8/8/2021 | | @ | ChN | W | Rendon, A | 5 | 4 | 69 | 31 | .690 | 8-2 | W3 | 100 |
| 8/9/2021 | | @ | ChN | L | | 3 | 9 | 69 | 32 | .683 | 8-2 | L1 | 101 |
| 8/10/2021 | | @ | ChN | L | | 5 | 6 | 69 | 33 | .676 | 7-3 | L2 | 102 |
| 8/11/2021 | | @ | Mil | W | Barnhart, T | 10 | 1 | 70 | 33 | .680 | 7-3 | W1 | 103 |
| 8/12/2021 | | @ | Mil | W | Barnhart, T | 5 | 3 | 71 | 33 | .683 | 7-3 | W2 | 104 |
| 8/13/2021 | | @ | Mil | W | Yastrzemski, M | 8 | 0 | 72 | 33 | .686 | 7-3 | W3 | 105 |
| 8/14/2021 | | | Mil | L | | 7 | 12 | 72 | 34 | .679 | 6-4 | L1 | 106 |
| 8/15/2021 | | | Mil | W | Nimmo, B | 3 | 2 | 73 | 34 | .682 | 7-3 | W1 | 107 |
| 8/16/2021 | | | Mil | W | Seager, C | 9 | 8 | 74 | 34 | .685 | 7-3 | W2 | 108 |
| 8/18/2021 | | | Cin | W | Rendon, A | 5 | 2 | 75 | 34 | .688 | 7-3 | W3 | 109 |
| 8/19/2021 | | | Cin | L | | 4 | 8 | 75 | 35 | .682 | 6-4 | L1 | 110 |
| 8/20/2021 | | | Cin | L | | 4 | 10 | 75 | 36 | .676 | 6-4 | L2 | 111 |
| 8/21/2021 | | @ | Cin | L | | 7 | 12 | 75 | 37 | .670 | 6-4 | L3 | 112 |
| 8/22/2021 | | @ | Cin | L | | 7 | 10 | 75 | 38 | .664 | 5-5 | L4 | 113 |
| 8/23/2021 | | @ | Cin | L | | 2 | 8 | 75 | 39 | .658 | 4-6 | L5 | 114 |
| 8/24/2021 | | @ | Tor | W | Rendon, A | 8 | 0 | 76 | 39 | .661 | 4-6 | W1 | 115 |
| 8/25/2021 | | @ | Tor | L | | 3 | 6 | 76 | 40 | .655 | 4-6 | L1 | 116 |
| 8/26/2021 | | @ | Tor | W | Rendon, A | 6 | 4 | 77 | 40 | .658 | 4-6 | W1 | 117 |
| 8/27/2021 | | | Tor | L | | 4 | 5 | 77 | 41 | .653 | 3-7 | L1 | 118 |
| 8/28/2021 | | | Tor | W | Yastrzemski, M | 4 | 1 | 78 | 41 | .655 | 3-7 | W1 | 119 |
| 8/29/2021 | | | Tor | W | Myers, W | 4 | 0 | 79 | 41 | .658 | 4-6 | W2 | 120 |
| 8/31/2021 | | | SF | W | | 9 | 5 | 80 | 41 | .661 | 5-5 | W3 | 121 |
| 9/1/2021 | | | SF | W | Belt, B | 10 | 8 | 81 | 41 | .664 | 6-4 | W4 | 122 |
| 9/2/2021 | | | SF | L | | 7 | 8 | 81 | 42 | .659 | 6-4 | L1 | 123 |
| 9/3/2021 | | @ | SF | L | | 3 | 5 | 81 | 43 | .653 | 6-4 | L2 | 124 |
| 9/4/2021 | | @ | SF | W | Belt, B | 10 | 8 | 82 | 43 | .656 | 6-4 | W1 | 125 |
| 9/5/2021 | | @ | SF | L | | 2 | 3 | 82 | 44 | .651 | 6-4 | L1 | 126 |
| 9/7/2021 | | @ | Was | W | Lux, G | 5 | 3 | 83 | 44 | .654 | 6-4 | W1 | 127 |
| 9/8/2021 | | @ | Was | L | | 3 | 9 | 83 | 45 | .648 | 6-4 | L1 | 128 |
| 9/9/2021 | | @ | Was | W | Flores, W | 2 | 1 | 84 | 45 | .651 | 6-4 | W1 | 129 |
| 9/10/2021 | | | Was | W | Flores, W | 13 | 11 | 85 | 45 | .654 | 6-4 | W2 | 130 |
| 9/11/2021 | | | Was | L | | 1 | 5 | 85 | 46 | .649 | 5-5 | L1 | 131 |
| 9/12/2021 | | | Was | W | Cervelli, F | 9 | 8 | 86 | 46 | .652 | 5-5 | W1 | 132 |