Team game results - 2021 Cincinnati Reds
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/16/2021 | | | NYM | W | 9-7 | | deGrom, J | R | deGrom, J | Rodriguez, R | Alcantara, S | R |
| 4/17/2021 | | | NYM | W | 3-0 | | Gray, S | R | Gray, S | | Nola, A | R |
| 4/18/2021 | | | NYM | L | 4-6 | | Davies, Z | R | Davies, Z | | Martinez, C | R |
| 4/19/2021 | | @ | NYM | L | 3-6 | | Anderson, B | L | Hoyt, J | | Peterson, D | L |
| 4/20/2021 | | @ | NYM | W | 3-2 | | Shoemaker, M | R | Treinen, B | Rodriguez, R | Hernandez, E | R |
| 4/21/2021 | | @ | NYM | W | 5-3 | | deGrom, J | R | deGrom, J | Watson, T | Alcantara, S | R |
| 4/23/2021 | | @ | Was | W | 6-0 | | Davies, Z | R | Davies, Z | | Gonsolin, T | R |
| 4/24/2021 | | @ | Was | W | 10-4 | | Gray, S | R | Gray, S | | Eflin, Z | R |
| 4/25/2021 | | @ | Was | L | 5-11 | | Anderson, B | L | Treinen, B | | Paddack, C | R |
| 4/26/2021 | | | Was | W | 11-2 | | Shoemaker, M | R | Shoemaker, M | | Sanchez, S | R |
| 4/27/2021 | | | Was | L | 3-5 | | deGrom, J | R | deGrom, J | | Urias, J | L |
| 4/28/2021 | | | Was | W | 10-3 | | Davies, Z | R | Davies, Z | | Bumgarner, M | L |
| 4/29/2021 | | | Pit | L | 2-3 | | Gray, S | R | Watson, T | | Weaver, L | R |
| 4/30/2021 | | | Pit | W | 6-2 | | Anderson, B | L | Anderson, B | Rodriguez, R | Hudson, D | R |
| 5/1/2021 | | | Pit | W | 8-7 | | Shoemaker, M | R | Treinen, B | | Burnes, C | R |
| 5/2/2021 | | @ | Pit | L | 3-7 | | deGrom, J | R | deGrom, J | | Wheeler, Z | R |
| 5/3/2021 | | @ | Pit | L | 3-4 | 11 | Davies, Z | R | Dayton, G | | Giolito, L | R |
| 5/4/2021 | | @ | Pit | L | 9-10 | | Gray, S | R | Almonte, Y | | Weaver, L | R |
| 5/6/2021 | | @ | Mia | W | 6-5 | | Anderson, B | L | Watson, T | Adam, J | Fiers, M | R |
| 5/7/2021 | | @ | Mia | W | 8-2 | | deGrom, J | R | deGrom, J | | Anderson, T | L |
| 5/8/2021 | | @ | Mia | W | 5-0 | | Davies, Z | R | Davies, Z | | Miley, W | L |
| 5/9/2021 | | | Mia | W | 5-4 | | Shoemaker, M | R | Shoemaker, M | Adam, J | Roark, T | R |
| 5/10/2021 | | | Mia | W | 2-0 | | Gray, S | R | Gray, S | Rodriguez, R | Hendricks, K | R |
| 5/11/2021 | | | Mia | W | 5-4 | | Anderson, B | L | Treinen, B | Almonte, Y | Ryu, H | L |
| 5/12/2021 | | | SF | W | 8-0 | | deGrom, J | R | deGrom, J | | Wainwright, A | R |
| 5/13/2021 | | | SF | L | 3-4 | | Davies, Z | R | Rodriguez, R | | Castillo, L | R |
| 5/14/2021 | | | SF | L | 2-9 | | Shoemaker, M | R | Shoemaker, M | | Alzolay, A | R |
| 5/15/2021 | | @ | SF | L | 2-3 | | Gray, S | R | Watson, T | | Gallen, Z | R |
| 5/16/2021 | | @ | SF | L | 2-4 | | Anderson, B | L | Almonte, Y | | Marquez, G | R |
| 5/17/2021 | | @ | SF | W | 8-3 | | deGrom, J | R | deGrom, J | | Lorenzen, M | R |
| 5/19/2021 | | @ | LA | L | 1-3 | | Shoemaker, M | R | Shoemaker, M | | Mills, A | R |
| 5/20/2021 | | @ | LA | L | 1-3 | | Davies, Z | R | Davies, Z | | Bauer, T | R |
| 5/21/2021 | | @ | LA | W | 5-4 | 11 | Gray, S | R | Hoyt, J | Almonte, Y | Maeda, K | R |
| 5/22/2021 | | | LA | L | 6-10 | | deGrom, J | R | Treinen, B | | Kershaw, C | L |
| 5/23/2021 | | | LA | L | 10-14 | | Anderson, B | L | Almonte, Y | | Senzatela, A | R |
| 5/24/2021 | | | LA | L | 3-6 | | Shoemaker, M | R | Shoemaker, M | | Mills, A | R |
| 5/26/2021 | | | ChN | W | 5-4 | | Brault, S | L | Almonte, Y | Dayton, G | Fried, M | L |
| 5/27/2021 | | | ChN | W | 4-3 | | Davies, Z | R | Davies, Z | Rodriguez, R | Mahle, T | R |
| 5/28/2021 | | | ChN | L | 2-4 | | Gray, S | R | Gray, S | | Richards, G | R |
| 5/29/2021 | | @ | ChN | W | 6-1 | | deGrom, J | R | deGrom, J | | Freeland, K | L |
| 5/30/2021 | | @ | ChN | L | 0-2 | | Anderson, B | L | Anderson, B | | Woodruff, B | R |
| 5/31/2021 | | @ | ChN | L | 9-10 | | Brault, S | L | Rodriguez, R | | Fried, M | L |
| 6/1/2021 | | @ | StL | W | 29-6 | | Davies, Z | R | Davies, Z | | Gausman, K | R |
| 6/2/2021 | | @ | StL | W | 8-7 | 12 | Gray, S | R | Treinen, B | Almonte, Y | Castellani, R | R |
| 6/3/2021 | | @ | StL | L | 2-3 | 10 | deGrom, J | R | Dayton, G | | Cole, G | R |
| 6/4/2021 | | | StL | L | 10-11 | | Anderson, B | L | Romo, S | | Kuhl, C | R |
| 6/5/2021 | | | StL | L | 2-4 | | Brault, S | L | Romo, S | | Lynn, L | R |
| 6/6/2021 | | | StL | L | 8-9 | | Davies, Z | R | Davies, Z | | Gausman, K | R |
| 6/8/2021 | | | Mil | W | 6-3 | | Gray, S | R | Almonte, Y | Treinen, B | Newcomb, S | L |
| 6/9/2021 | | | Mil | W | 7-6 | | deGrom, J | R | Watson, T | | Rogers, T | L |
| 6/10/2021 | | | Mil | W | 3-1 | 10 | Brault, S | L | Watson, T | | Lamet, D | R |
| 6/11/2021 | | @ | Mil | L | 4-7 | | Gray, S | R | Gray, S | | Cueto, J | R |
| 6/12/2021 | | @ | Mil | W | 5-3 | | Davies, Z | R | Davies, Z | Treinen, B | Smyly, D | L |
| 6/13/2021 | | @ | Mil | W | 15-10 | | Anderson, B | L | Romo, S | Treinen, B | Newcomb, S | L |
| 6/15/2021 | | @ | Atl | L | 6-8 | | deGrom, J | R | deGrom, J | | Fedde, E | R |
| 6/16/2021 | | @ | Atl | W | 9-3 | | Brault, S | L | Brault, S | | May, D | R |
| 6/17/2021 | | @ | Atl | W | 5-1 | | Gray, S | R | Gray, S | | Glasnow, T | R |
| 6/18/2021 | | | Atl | W | 8-2 | | Davies, Z | R | Davies, Z | | Heaney, A | L |
| 6/19/2021 | | | Atl | W | 13-5 | | Anderson, B | L | Almonte, Y | | Wright, K | R |
| 6/20/2021 | | | Atl | W | 14-3 | | deGrom, J | R | Turley, N | | Sanchez, A | R |
| 6/22/2021 | | | Tor | W | 7-2 | | Brault, S | L | Brault, S | | Scherzer, M | R |
| 6/23/2021 | | | Tor | W | 2-1 | | Gray, S | R | Gray, S | Treinen, B | Kim, K | L |
| 6/24/2021 | | | Tor | L | 2-4 | | Davies, Z | R | Davies, Z | | Lopez, P | R |
| 6/25/2021 | | @ | Tor | L | 0-3 | | deGrom, J | R | deGrom, J | | Darvish, Y | R |
| 6/26/2021 | | @ | Tor | W | 2-1 | | Cahill, T | R | Rodriguez, R | Romo, S | Corbin, P | L |
| 6/27/2021 | | @ | Tor | W | 5-1 | | Brault, S | L | Brault, S | | Scherzer, M | R |
| 6/28/2021 | | @ | StL | L | 6-11 | | Gray, S | R | Gray, S | | Cole, G | R |
| 7/3/2021 | | | Was | W | 13-1 | | deGrom, J | R | deGrom, J | | Urias, J | L |
| 7/4/2021 | | | Was | W | 4-1 | | Davies, Z | R | Davies, Z | Treinen, B | Paddack, C | R |
| 7/5/2021 | | | Was | W | 9-6 | | Gray, S | R | Gray, S | Dayton, G | Bumgarner, M | L |
| 7/6/2021 | | @ | Was | L | 2-12 | | Brault, S | L | Brault, S | | Gonsolin, T | R |
| 7/7/2021 | | @ | Was | L | 8-14 | | Shoemaker, M | R | Shoemaker, M | | Eflin, Z | R |
| 7/8/2021 | | @ | Was | W | 4-2 | | deGrom, J | R | deGrom, J | Rodriguez, R | Sanchez, S | R |
| 7/9/2021 | | | SF | W | 6-3 | | Davies, Z | R | Davies, Z | Hoyt, J | Castillo, L | R |
| 7/10/2021 | | | SF | W | 10-4 | | Gray, S | R | Romo, S | | Gallen, Z | R |
| 7/11/2021 | | | SF | W | 4-3 | | Brault, S | L | Adam, J | Almonte, Y | Wainwright, A | R |
| 7/13/2021 | | @ | SF | W | 8-2 | | deGrom, J | R | deGrom, J | | Marquez, G | R |
| 7/14/2021 | | @ | SF | L | 1-4 | | Davies, Z | R | Davies, Z | | Castillo, L | R |
| 7/15/2021 | | @ | SF | W | 5-4 | | Shoemaker, M | R | Shoemaker, M | Treinen, B | Gallen, Z | R |
| 7/16/2021 | | @ | Tor | L | 2-10 | | Gray, S | R | Gray, S | | Lopez, P | R |
| 7/17/2021 | | @ | Tor | W | 7-5 | 10 | Brault, S | L | Treinen, B | | Scherzer, M | R |
| 7/18/2021 | | @ | Tor | L | 3-8 | | deGrom, J | R | deGrom, J | | Darvish, Y | R |
| 7/19/2021 | | | Tor | W | 3-2 | | Davies, Z | R | Rodriguez, R | | Kim, K | L |
| 7/20/2021 | | | Tor | W | 3-2 | 10 | Shoemaker, M | R | Treinen, B | | Anderson, I | R |
| 7/21/2021 | | | Tor | W | 9-6 | | Gray, S | R | Hoyt, J | | Lopez, P | R |
| 7/23/2021 | | @ | Mil | L | 2-4 | | Brault, S | L | Brault, S | | Kelly, M | R |
| 7/24/2021 | | @ | Mil | L | 3-6 | | deGrom, J | R | Romo, S | | Cueto, J | R |
| 7/25/2021 | | @ | Mil | W | 8-7 | 10 | Davies, Z | R | Romo, S | Dayton, G | Lindblom, J | R |
| 7/26/2021 | | | Mil | W | 4-1 | | Shoemaker, M | R | Shoemaker, M | Treinen, B | Smyly, D | L |
| 7/27/2021 | | | Mil | L | 3-9 | | Gray, S | R | Gray, S | | Lamet, D | R |
| 7/28/2021 | | | Mil | L | 3-11 | | Brault, S | L | Brault, S | | Peralta, F | R |
| 7/29/2021 | | | ChN | W | 5-4 | | deGrom, J | R | deGrom, J | Watson, T | Woodruff, B | R |
| 7/30/2021 | | | ChN | W | 9-3 | | Davies, Z | R | Davies, Z | | Freeland, K | L |
| 7/31/2021 | | | ChN | W | 5-3 | | Shoemaker, M | R | Romo, S | Rodriguez, R | Gray, J | R |
| 8/1/2021 | | @ | ChN | L | 9-13 | | Gray, S | R | Adam, J | | Webb, L | R |
| 8/2/2021 | | @ | ChN | L | 6-13 | | Brault, S | L | Treinen, B | | Mahle, T | R |
| 8/3/2021 | | @ | ChN | L | 8-9 | | deGrom, J | R | deGrom, J | | Woodruff, B | R |
| 8/5/2021 | | @ | NYM | L | 3-4 | 10 | Shoemaker, M | R | Romo, S | | Alcantara, S | R |
| 8/6/2021 | | @ | NYM | W | 5-0 | | Davies, Z | R | Davies, Z | | Musgrove, J | R |
| 8/7/2021 | | @ | NYM | W | 6-4 | | Cahill, T | R | Romo, S | Watson, T | Peterson, D | L |
| 8/8/2021 | | | NYM | W | 7-6 | | Brault, S | L | Turley, N | Rodriguez, R | Brubaker, J | R |
| 8/9/2021 | | | NYM | W | 3-2 | | deGrom, J | R | Treinen, B | | Nola, A | R |
| 8/10/2021 | | | NYM | W | 6-3 | | Shoemaker, M | R | Hoyt, J | Turley, N | Alcantara, S | R |
| 8/11/2021 | | | Atl | W | 6-3 | | Anderson, B | L | Almonte, Y | Treinen, B | May, D | R |
| 8/12/2021 | | | Atl | W | 16-0 | | Davies, Z | R | Davies, Z | | Fedde, E | R |
| 8/13/2021 | | | Atl | W | 10-1 | | Gray, S | R | Gray, S | | Sanchez, A | R |
| 8/14/2021 | | @ | Atl | W | 4-1 | | Brault, S | L | Almonte, Y | | Glasnow, T | R |
| 8/15/2021 | | @ | Atl | L | 2-4 | | deGrom, J | R | deGrom, J | | Heaney, A | L |
| 8/16/2021 | | @ | Atl | L | 1-3 | | Anderson, B | L | Anderson, B | | May, D | R |
| 8/18/2021 | | @ | Pit | L | 2-5 | | Davies, Z | R | Davies, Z | | Burnes, C | R |
| 8/19/2021 | | @ | Pit | W | 8-4 | | Gray, S | R | Gray, S | | Hudson, D | R |
| 8/20/2021 | | @ | Pit | W | 10-4 | 11 | Brault, S | L | Watson, T | | Wheeler, Z | R |
| 8/21/2021 | | | Pit | W | 12-7 | | deGrom, J | R | deGrom, J | | Giolito, L | R |
| 8/22/2021 | | | Pit | W | 10-7 | | Anderson, B | L | Anderson, B | | Weaver, L | R |
| 8/23/2021 | | | Pit | W | 8-2 | | Davies, Z | R | Davies, Z | | Burnes, C | R |
| 8/24/2021 | | | LA | L | 4-5 | | Gray, S | R | Rodriguez, R | | Maeda, K | R |
| 8/25/2021 | | | LA | W | 8-4 | | Brault, S | L | Brault, S | Watson, T | Kershaw, C | L |
| 8/26/2021 | | | LA | W | 7-6 | | deGrom, J | R | Turley, N | Romo, S | Senzatela, A | R |
| 8/27/2021 | | @ | LA | L | 5-7 | | Anderson, B | L | Anderson, B | | Mills, A | R |
| 8/28/2021 | | @ | LA | L | 0-2 | | Davies, Z | R | Davies, Z | | Bauer, T | R |
| 8/29/2021 | | @ | LA | W | 5-4 | | Gray, S | R | Gray, S | Rodriguez, R | Maeda, K | R |
| 8/31/2021 | | @ | StL | W | 11-2 | | deGrom, J | R | deGrom, J | | Lynn, L | R |
| 9/1/2021 | | @ | StL | W | 2-1 | | Brault, S | L | Almonte, Y | Watson, T | Gausman, K | R |
| 9/2/2021 | | @ | StL | W | 4-2 | 10 | Anderson, B | L | Watson, T | Romo, S | Cole, G | R |
| 9/3/2021 | | | StL | L | 5-9 | 12 | Davies, Z | R | Turley, N | | Kuhl, C | R |
| 9/4/2021 | | | StL | W | 6-1 | | Gray, S | R | Gray, S | | Castellani, R | R |
| 9/5/2021 | | | StL | W | 6-5 | | deGrom, J | R | Romo, S | Treinen, B | Lynn, L | R |
| 9/7/2021 | | | Mia | L | 3-5 | | Anderson, B | L | Romo, S | | Hendricks, K | R |
| 9/8/2021 | | | Mia | W | 5-4 | 10 | Davies, Z | R | Dayton, G | | Ryu, H | L |
| 9/9/2021 | | | Mia | W | 11-3 | | Gray, S | R | Gray, S | Hill, T | Anderson, T | L |
| 9/10/2021 | | @ | Mia | W | 8-1 | | deGrom, J | R | deGrom, J | | Roark, T | R |
| 9/11/2021 | | @ | Mia | L | 3-5 | 10 | Cahill, T | R | Watson, T | | Hendricks, K | R |
| 9/12/2021 | | @ | Mia | L | 2-3 | | Anderson, B | L | Anderson, B | | Castano, D | L |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/16/2021 | | | NYM | W | Verdugo, A | 9 | 7 | 1 | 0 | 1.000 | 1-0 | W1 | 1 |
| 4/17/2021 | | | NYM | W | Happ, I | 3 | 0 | 2 | 0 | 1.000 | 2-0 | W2 | 2 |
| 4/18/2021 | | | NYM | L | | 4 | 6 | 2 | 1 | .667 | 2-1 | L1 | 3 |
| 4/19/2021 | | @ | NYM | L | | 3 | 6 | 2 | 2 | .500 | 2-2 | L2 | 4 |
| 4/20/2021 | | @ | NYM | W | Happ, I | 3 | 2 | 3 | 2 | .600 | 3-2 | W1 | 5 |
| 4/21/2021 | | @ | NYM | W | Davis, J | 5 | 3 | 4 | 2 | .667 | 4-2 | W2 | 6 |
| 4/23/2021 | | @ | Was | W | Pina, M | 6 | 0 | 5 | 2 | .714 | 5-2 | W3 | 7 |
| 4/24/2021 | | @ | Was | W | Hayes, K | 10 | 4 | 6 | 2 | .750 | 6-2 | W4 | 8 |
| 4/25/2021 | | @ | Was | L | | 5 | 11 | 6 | 3 | .667 | 6-3 | L1 | 9 |
| 4/26/2021 | | | Was | W | Davis, J | 11 | 2 | 7 | 3 | .700 | 7-3 | W1 | 10 |
| 4/27/2021 | | | Was | L | | 3 | 5 | 7 | 4 | .636 | 6-4 | L1 | 11 |
| 4/28/2021 | | | Was | W | Realmuto, J | 10 | 3 | 8 | 4 | .667 | 6-4 | W1 | 12 |
| 4/29/2021 | | | Pit | L | | 2 | 3 | 8 | 5 | .615 | 6-4 | L1 | 13 |
| 4/30/2021 | | | Pit | W | Ruf, D | 6 | 2 | 9 | 5 | .643 | 7-3 | W1 | 14 |
| 5/1/2021 | | | Pit | W | Davis, J | 8 | 7 | 10 | 5 | .667 | 7-3 | W2 | 15 |
| 5/2/2021 | | @ | Pit | L | | 3 | 7 | 10 | 6 | .625 | 6-4 | L1 | 16 |
| 5/3/2021 | | @ | Pit | L | | 3 | 4 | 10 | 7 | .588 | 5-5 | L2 | 17 |
| 5/4/2021 | | @ | Pit | L | | 9 | 10 | 10 | 8 | .556 | 4-6 | L3 | 18 |
| 5/6/2021 | | @ | Mia | W | Martinez, J | 6 | 5 | 11 | 8 | .579 | 5-5 | W1 | 19 |
| 5/7/2021 | | @ | Mia | W | Happ, I | 8 | 2 | 12 | 8 | .600 | 5-5 | W2 | 20 |
| 5/8/2021 | | @ | Mia | W | Martinez, J | 5 | 0 | 13 | 8 | .619 | 6-4 | W3 | 21 |
| 5/9/2021 | | | Mia | W | Ruf, D | 5 | 4 | 14 | 8 | .636 | 6-4 | W4 | 22 |
| 5/10/2021 | | | Mia | W | McNeil, J | 2 | 0 | 15 | 8 | .652 | 7-3 | W5 | 23 |
| 5/11/2021 | | | Mia | W | Arcia, O | 5 | 4 | 16 | 8 | .667 | 7-3 | W6 | 24 |
| 5/12/2021 | | | SF | W | Cronenworth, J | 8 | 0 | 17 | 8 | .680 | 7-3 | W7 | 25 |
| 5/13/2021 | | | SF | L | | 3 | 4 | 17 | 9 | .654 | 7-3 | L1 | 26 |
| 5/14/2021 | | | SF | L | | 2 | 9 | 17 | 10 | .630 | 7-3 | L2 | 27 |
| 5/15/2021 | | @ | SF | L | | 2 | 3 | 17 | 11 | .607 | 7-3 | L3 | 28 |
| 5/16/2021 | | @ | SF | L | | 2 | 4 | 17 | 12 | .586 | 6-4 | L4 | 29 |
| 5/17/2021 | | @ | SF | W | Edman, T | 8 | 3 | 18 | 12 | .600 | 6-4 | W1 | 30 |
| 5/19/2021 | | @ | LA | L | | 1 | 3 | 18 | 13 | .581 | 5-5 | L1 | 31 |
| 5/20/2021 | | @ | LA | L | | 1 | 3 | 18 | 14 | .563 | 4-6 | L2 | 32 |
| 5/21/2021 | | @ | LA | W | Martinez, J | 5 | 4 | 19 | 14 | .576 | 4-6 | W1 | 33 |
| 5/22/2021 | | | LA | L | | 6 | 10 | 19 | 15 | .559 | 3-7 | L1 | 34 |
| 5/23/2021 | | | LA | L | | 10 | 14 | 19 | 16 | .543 | 2-8 | L2 | 35 |
| 5/24/2021 | | | LA | L | | 3 | 6 | 19 | 17 | .528 | 2-8 | L3 | 36 |
| 5/26/2021 | | | ChN | W | Rojas, M | 5 | 4 | 20 | 17 | .541 | 3-7 | W1 | 37 |
| 5/27/2021 | | | ChN | W | Guillorme, L | 4 | 3 | 21 | 17 | .553 | 4-6 | W2 | 38 |
| 5/28/2021 | | | ChN | L | | 2 | 4 | 21 | 18 | .538 | 4-6 | L1 | 39 |
| 5/29/2021 | | @ | ChN | W | Ruf, D | 6 | 1 | 22 | 18 | .550 | 4-6 | W1 | 40 |
| 5/30/2021 | | @ | ChN | L | | 0 | 2 | 22 | 19 | .537 | 4-6 | L1 | 41 |
| 5/31/2021 | | @ | ChN | L | | 9 | 10 | 22 | 20 | .524 | 4-6 | L2 | 42 |
| 6/1/2021 | | @ | StL | W | Cronenworth, J | 29 | 6 | 23 | 20 | .535 | 4-6 | W1 | 43 |
| 6/2/2021 | | @ | StL | W | | 8 | 7 | 24 | 20 | .545 | 5-5 | W2 | 44 |
| 6/3/2021 | | @ | StL | L | | 2 | 3 | 24 | 21 | .533 | 5-5 | L1 | 45 |
| 6/4/2021 | | | StL | L | | 10 | 11 | 24 | 22 | .522 | 5-5 | L2 | 46 |
| 6/5/2021 | | | StL | L | | 2 | 4 | 24 | 23 | .511 | 4-6 | L3 | 47 |
| 6/6/2021 | | | StL | L | | 8 | 9 | 24 | 24 | .500 | 3-7 | L4 | 48 |
| 6/8/2021 | | | Mil | W | Martinez, J | 6 | 3 | 25 | 24 | .510 | 4-6 | W1 | 49 |
| 6/9/2021 | | | Mil | W | Hayes, K | 7 | 6 | 26 | 24 | .520 | 4-6 | W2 | 50 |
| 6/10/2021 | | | Mil | W | Arozarena, R | 3 | 1 | 27 | 24 | .529 | 5-5 | W3 | 51 |
| 6/11/2021 | | @ | Mil | L | | 4 | 7 | 27 | 25 | .519 | 5-5 | L1 | 52 |
| 6/12/2021 | | @ | Mil | W | Martinez, J | 5 | 3 | 28 | 25 | .528 | 5-5 | W1 | 53 |
| 6/13/2021 | | @ | Mil | W | Hayes, K | 15 | 10 | 29 | 25 | .537 | 5-5 | W2 | 54 |
| 6/15/2021 | | @ | Atl | L | | 6 | 8 | 29 | 26 | .527 | 5-5 | L1 | 55 |
| 6/16/2021 | | @ | Atl | W | Cronenworth, J | 9 | 3 | 30 | 26 | .536 | 6-4 | W1 | 56 |
| 6/17/2021 | | @ | Atl | W | Martinez, J | 5 | 1 | 31 | 26 | .544 | 7-3 | W2 | 57 |
| 6/18/2021 | | | Atl | W | Arozarena, R | 8 | 2 | 32 | 26 | .552 | 8-2 | W3 | 58 |
| 6/19/2021 | | | Atl | W | Martinez, J | 13 | 5 | 33 | 26 | .559 | 8-2 | W4 | 59 |
| 6/20/2021 | | | Atl | W | Happ, I | 14 | 3 | 34 | 26 | .567 | 8-2 | W5 | 60 |
| 6/22/2021 | | | Tor | W | Happ, I | 7 | 2 | 35 | 26 | .574 | 8-2 | W6 | 61 |
| 6/23/2021 | | | Tor | W | Arozarena, R | 2 | 1 | 36 | 26 | .581 | 9-1 | W7 | 62 |
| 6/24/2021 | | | Tor | L | | 2 | 4 | 36 | 27 | .571 | 8-2 | L1 | 63 |
| 6/25/2021 | | @ | Tor | L | | 0 | 3 | 36 | 28 | .563 | 7-3 | L2 | 64 |
| 6/26/2021 | | @ | Tor | W | Rojas, M | 2 | 1 | 37 | 28 | .569 | 8-2 | W1 | 65 |
| 6/27/2021 | | @ | Tor | W | Cronenworth, J | 5 | 1 | 38 | 28 | .576 | 8-2 | W2 | 66 |
| 6/28/2021 | | @ | StL | L | | 6 | 11 | 38 | 29 | .567 | 7-3 | L1 | 67 |
| 7/3/2021 | | | Was | W | Hayes, K | 13 | 1 | 39 | 29 | .574 | 7-3 | W1 | 68 |
| 7/4/2021 | | | Was | W | Knapp, A | 4 | 1 | 40 | 29 | .580 | 7-3 | W2 | 69 |
| 7/5/2021 | | | Was | W | Arozarena, R | 9 | 6 | 41 | 29 | .586 | 7-3 | W3 | 70 |
| 7/6/2021 | | @ | Was | L | | 2 | 12 | 41 | 30 | .577 | 6-4 | L1 | 71 |
| 7/7/2021 | | @ | Was | L | | 8 | 14 | 41 | 31 | .569 | 5-5 | L2 | 72 |
| 7/8/2021 | | @ | Was | W | Hayes, K | 4 | 2 | 42 | 31 | .575 | 6-4 | W1 | 73 |
| 7/9/2021 | | | SF | W | Arozarena, R | 6 | 3 | 43 | 31 | .581 | 7-3 | W2 | 74 |
| 7/10/2021 | | | SF | W | McNeil, J | 10 | 4 | 44 | 31 | .587 | 7-3 | W3 | 75 |
| 7/11/2021 | | | SF | W | McNeil, J | 4 | 3 | 45 | 31 | .592 | 7-3 | W4 | 76 |
| 7/13/2021 | | @ | SF | W | | 8 | 2 | 46 | 31 | .597 | 8-2 | W5 | 77 |
| 7/14/2021 | | @ | SF | L | | 1 | 4 | 46 | 32 | .590 | 7-3 | L1 | 78 |
| 7/15/2021 | | @ | SF | W | Happ, I | 5 | 4 | 47 | 32 | .595 | 7-3 | W1 | 79 |
| 7/16/2021 | | @ | Tor | L | | 2 | 10 | 47 | 33 | .587 | 6-4 | L1 | 80 |
| 7/17/2021 | | @ | Tor | W | Ruf, D | 7 | 5 | 48 | 33 | .593 | 7-3 | W1 | 81 |
| 7/18/2021 | | @ | Tor | L | | 3 | 8 | 48 | 34 | .585 | 7-3 | L1 | 82 |
| 7/19/2021 | | | Tor | W | Hayes, K | 3 | 2 | 49 | 34 | .590 | 7-3 | W1 | 83 |
| 7/20/2021 | | | Tor | W | Knapp, A | 3 | 2 | 50 | 34 | .595 | 7-3 | W2 | 84 |
| 7/21/2021 | | | Tor | W | Edman, T | 9 | 6 | 51 | 34 | .600 | 7-3 | W3 | 85 |
| 7/23/2021 | | @ | Mil | L | | 2 | 4 | 51 | 35 | .593 | 6-4 | L1 | 86 |
| 7/24/2021 | | @ | Mil | L | | 3 | 6 | 51 | 36 | .586 | 5-5 | L2 | 87 |
| 7/25/2021 | | @ | Mil | W | Rojas, M | 8 | 7 | 52 | 36 | .591 | 6-4 | W1 | 88 |
| 7/26/2021 | | | Mil | W | Rojas, M | 4 | 1 | 53 | 36 | .596 | 6-4 | W2 | 89 |
| 7/27/2021 | | | Mil | L | | 3 | 9 | 53 | 37 | .589 | 6-4 | L1 | 90 |
| 7/28/2021 | | | Mil | L | | 3 | 11 | 53 | 38 | .582 | 5-5 | L2 | 91 |
| 7/29/2021 | | | ChN | W | McNeil, J | 5 | 4 | 54 | 38 | .587 | 6-4 | W1 | 92 |
| 7/30/2021 | | | ChN | W | McNeil, J | 9 | 3 | 55 | 38 | .591 | 6-4 | W2 | 93 |
| 7/31/2021 | | | ChN | W | Realmuto, J | 5 | 3 | 56 | 38 | .596 | 6-4 | W3 | 94 |
| 8/1/2021 | | @ | ChN | L | | 9 | 13 | 56 | 39 | .589 | 5-5 | L1 | 95 |
| 8/2/2021 | | @ | ChN | L | | 6 | 13 | 56 | 40 | .583 | 5-5 | L2 | 96 |
| 8/3/2021 | | @ | ChN | L | | 8 | 9 | 56 | 41 | .577 | 5-5 | L3 | 97 |
| 8/5/2021 | | @ | NYM | L | | 3 | 4 | 56 | 42 | .571 | 4-6 | L4 | 98 |
| 8/6/2021 | | @ | NYM | W | Arcia, O | 5 | 0 | 57 | 42 | .576 | 4-6 | W1 | 99 |
| 8/7/2021 | | @ | NYM | W | Davis, J | 6 | 4 | 58 | 42 | .580 | 5-5 | W2 | 100 |
| 8/8/2021 | | | NYM | W | Edman, T | 7 | 6 | 59 | 42 | .584 | 6-4 | W3 | 101 |
| 8/9/2021 | | | NYM | W | Guillorme, L | 3 | 2 | 60 | 42 | .588 | 6-4 | W4 | 102 |
| 8/10/2021 | | | NYM | W | Ruf, D | 6 | 3 | 61 | 42 | .592 | 6-4 | W5 | 103 |
| 8/11/2021 | | | Atl | W | Guillorme, L | 6 | 3 | 62 | 42 | .596 | 6-4 | W6 | 104 |
| 8/12/2021 | | | Atl | W | Rojas, M | 16 | 0 | 63 | 42 | .600 | 7-3 | W7 | 105 |
| 8/13/2021 | | | Atl | W | Realmuto, J | 10 | 1 | 64 | 42 | .604 | 8-2 | W8 | 106 |
| 8/14/2021 | | @ | Atl | W | Davis, J | 4 | 1 | 65 | 42 | .607 | 9-1 | W9 | 107 |
| 8/15/2021 | | @ | Atl | L | | 2 | 4 | 65 | 43 | .602 | 9-1 | L1 | 108 |
| 8/16/2021 | | @ | Atl | L | | 1 | 3 | 65 | 44 | .596 | 8-2 | L2 | 109 |
| 8/18/2021 | | @ | Pit | L | | 2 | 5 | 65 | 45 | .591 | 7-3 | L3 | 110 |
| 8/19/2021 | | @ | Pit | W | Realmuto, J | 8 | 4 | 66 | 45 | .595 | 7-3 | W1 | 111 |
| 8/20/2021 | | @ | Pit | W | Knapp, A | 10 | 4 | 67 | 45 | .598 | 7-3 | W2 | 112 |
| 8/21/2021 | | | Pit | W | Happ, I | 12 | 7 | 68 | 45 | .602 | 7-3 | W3 | 113 |
| 8/22/2021 | | | Pit | W | Edman, T | 10 | 7 | 69 | 45 | .605 | 7-3 | W4 | 114 |
| 8/23/2021 | | | Pit | W | Verdugo, A | 8 | 2 | 70 | 45 | .609 | 7-3 | W5 | 115 |
| 8/24/2021 | | | LA | L | | 4 | 5 | 70 | 46 | .603 | 6-4 | L1 | 116 |
| 8/25/2021 | | | LA | W | Davis, J | 8 | 4 | 71 | 46 | .607 | 6-4 | W1 | 117 |
| 8/26/2021 | | | LA | W | Rojas, M | 7 | 6 | 72 | 46 | .610 | 7-3 | W2 | 118 |
| 8/27/2021 | | @ | LA | L | | 5 | 7 | 72 | 47 | .605 | 7-3 | L1 | 119 |
| 8/28/2021 | | @ | LA | L | | 0 | 2 | 72 | 48 | .600 | 7-3 | L2 | 120 |
| 8/29/2021 | | @ | LA | W | Davis, J | 5 | 4 | 73 | 48 | .603 | 7-3 | W1 | 121 |
| 8/31/2021 | | @ | StL | W | Pina, M | 11 | 2 | 74 | 48 | .607 | 7-3 | W2 | 122 |
| 9/1/2021 | | @ | StL | W | Happ, I | 2 | 1 | 75 | 48 | .610 | 7-3 | W3 | 123 |
| 9/2/2021 | | @ | StL | W | Realmuto, J | 4 | 2 | 76 | 48 | .613 | 7-3 | W4 | 124 |
| 9/3/2021 | | | StL | L | | 5 | 9 | 76 | 49 | .608 | 6-4 | L1 | 125 |
| 9/4/2021 | | | StL | W | Arcia, O | 6 | 1 | 77 | 49 | .611 | 7-3 | W1 | 126 |
| 9/5/2021 | | | StL | W | Martinez, J | 6 | 5 | 78 | 49 | .614 | 7-3 | W2 | 127 |
| 9/7/2021 | | | Mia | L | | 3 | 5 | 78 | 50 | .609 | 6-4 | L1 | 128 |
| 9/8/2021 | | | Mia | W | McNeil, J | 5 | 4 | 79 | 50 | .612 | 7-3 | W1 | 129 |
| 9/9/2021 | | | Mia | W | McNeil, J | 11 | 3 | 80 | 50 | .615 | 8-2 | W2 | 130 |
| 9/10/2021 | | @ | Mia | W | Hayes, K | 8 | 1 | 81 | 50 | .618 | 8-2 | W3 | 131 |
| 9/11/2021 | | @ | Mia | L | | 3 | 5 | 81 | 51 | .614 | 7-3 | L1 | 132 |
| 9/12/2021 | | @ | Mia | L | | 2 | 3 | 81 | 52 | .609 | 6-4 | L2 | 133 |